Immunoregulatory Abnormalities in Autoimmune Thyroid Diseases
نویسندگان
چکیده
منابع مشابه
Immunoregulatory abnormalities in autoimmune thyroid diseases.
We have investigated the ability of lymphocytes from normal subjects and patients with autoimmune thyroid diseases to respond to a thyroidal antigen (human thyroglobulin, hTG) and a non-thyroidal antigen (Keyhole limpet hemocyanin, KLH) in vitro, using a hapten (trinitrophenol, TNP)-carrier system. This system is based on the concept that the T helper cells which respond to hTG or KLH should st...
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Autoimmune thyroid disease (AITD) is the most common organ-specific autoimmune disorder affecting 2% to 5% of the population in Western countries. Clinical presentation varies from hyperthyroidism in Graves' Disease to hypothyroidism in Hashimoto's thyroiditis. While the exact etiology of thyroid autoimmunity is not known, interaction between genetic susceptibility and environmental factors app...
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ژورنال
عنوان ژورنال: Endocrinologia Japonica
سال: 1987
ISSN: 0013-7219,2185-6370
DOI: 10.1507/endocrj1954.34.203